TRANSCRIPTOME ANALYSIS REVEALS THE MECHANISM OF STROMAL CELL-DERIVED FACTOR-1 AND EXENDIN-4 SYNERGISTICALLY PROMOTED PERIODONTAL LIGAMENT STEM CELLS OSTEOGENIC DIFFERENTIATION

Stromal cell-derived factor-1 (SDF-1) and Exendin-4 Compressor Motor Start Relay (EX-4) play beneficial roles in promoting periodontal ligament stem cells (PDLSCs) osteogenic differentiation, while the detailed mechanism has not been clarified.In this study, we aimed to evaluate the biological mechanism of SDF-1 and EX-4 alone or synergistic applic

Investigating and understanding the impact of dust storms on wetland vegetation changes can lead to useful information for their Chestnut optimal management.In this study, the wind rose and hurricane rose diagrams of the research area were prepared using wind statistics of Ahvaz meteorological stations.Changes in vegetation cover of Shadegan wetlan

Introduction: Oral lichen planus (OLP) is a Coffee Decanters common chronic mucocutaneous disease.Patients with atrophic and erosive types of OLP often have symptoms of soreness, and require proper treatment.The main treatment for OLP has been the administration of topical or systemic corticosteroids.The objective of this study was to compare the e

Summary: Spliceosome machinery mutations are common early mutations in myeloid malignancies; however, effective targeted therapies against them are still lacking.In the current study, we used an in vitro high-throughput drug screen among four different isogenic cell lines and identified RKI-1447, a Rho-associated protein kinase Pumpkin inhibitor, a